Publications.

Huang N, Groover D, Damania B, Moody CA; Apoptotic caspases suppress an MDA5-driven IFN response during productive replication of human papillomavirus type 31. Proceedings of the National Academy of Sciences. 2022 Jul 11; 119(29). https://doi.org/10.1073/pnas.2200206119

Moody CA; Regulation of the Innate Immune Response during the Human Papillomavirus Life Cycle. Viruses. 2022, 14, 1797. https://doi.org/10.3390/v14081797

Moody CA, Rutala WA, Gergen MF, Anderson DJ, Sickbert-Bennett EE, Weber DJ; CDC Prevention Epicenters Program. Susceptibility of human papillomavirus 16 to disinfectants. Infect Control Hosp Epidemiol. 2021 Oct 1:1-2. doi: 10.1017/ice.2021.411. Epub ahead of print. PMID: 34593067.

Mac M, Moody CA. Epigenetic Regulation of the Human Papillomavirus Life Cycle. Pathogens. 2020 Jun 18;9(6):483. doi: 10.3390/pathogens9060483. PMID: 32570816; PMCID: PMC7350343.

Sitz J, Blanchet SA, Gameiro SF, Biquand E, Morgan TM, Galloy M, Dessapt J, Lavoie EG, Blondeau A, Smith BC, Mymryk JS, Moody CA, Fradet-Turcotte A. Human papillomavirus E7 oncoprotein targets RNF168 to hijack the host DNA damage response. Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19552-19562. doi: 10.1073/pnas.1906102116. Epub 2019 Sep 9. PMID: 31501315; PMCID: PMC6765264.

Moody CA. Impact of Replication Stress in Human Papillomavirus Pathogenesis. J Virol. 2019 Jan 4;93(2):e01012-17. doi: 10.1128/JVI.01012-17. PMID: 30355682; PMCID: PMC6321920.

Gautam D, Johnson BA, Mac M, Moody CA. SETD2-dependent H3K36me3 plays a critical role in epigenetic regulation of the HPV31 life cycle. PLoS Pathog. 2018 Oct 12;14(10):e1007367. doi: 10.1371/journal.ppat.1007367. PMID: 30312361; PMCID: PMC6200281.

Moody C, Robertson E. Editorial overview: Viruses and cancer. Curr Opin Virol. 2018 Oct;32:iv. doi: 10.1016/j.coviro.2018.11.003. PMID: 30473419.

Hopcraft SE, Moody CA, Damania B. Air-Liquid Interface System To Understand Epstein-Barr Virus-Associated Nasopharyngeal Carcinoma. mSphere. 2018 Jul 18;3(4):e00350-18. doi: 10.1128/mSphere.00350-18. PMID: 30021881; PMCID: PMC6052335.

Johnson BA, Aloor HL, Moody CA. The Rb binding domain of HPV31 E7 is required to maintain high levels of DNA repair factors in infected cells. Virology. 2017 Jan;500:22-34. doi: 10.1016/j.virol.2016.09.029. Epub 2016 Oct 19. PMID: 27770701; PMCID: PMC5541366.

Anacker DC, Moody CA. Modulation of the DNA damage response during the life cycle of human papillomaviruses. Virus Res. 2017 Mar 2;231:41-49. doi: 10.1016/j.virusres.2016.11.006. Epub 2016 Nov 9. PMID: 27836727; PMCID: PMC5325762.

Anacker DC, Aloor HL, Shepard CN, Lenzi GM, Johnson BA, Kim B, Moody CA. HPV31 utilizes the ATR-Chk1 pathway to maintain elevated RRM2 levels and a replication-competent environment in differentiating Keratinocytes. Virology. 2016 Dec;499:383-396. doi: 10.1016/j.virol.2016.09.028. Epub 2016 Oct 17. PMID: 27764728; PMCID: PMC5102796.

Chappell WH, Gautam D, Ok ST, Johnson BA, Anacker DC, Moody CA. Homologous Recombination Repair Factors Rad51 and BRCA1 Are Necessary for Productive Replication of Human Papillomavirus 31. J Virol. 2015 Dec 23;90(5):2639-52. doi: 10.1128/JVI.02495-15. PMID: 26699641; PMCID: PMC4810724.

Bentz GL, Moss CR 2nd, Whitehurst CB, Moody CA, Pagano JS. LMP1-Induced Sumoylation Influences the Maintenance of Epstein-Barr Virus Latency through KAP1. J Virol. 2015 Aug;89(15):7465-77. doi: 10.1128/JVI.00711-15. Epub 2015 May 6. PMID: 25948750; PMCID: PMC4505653.

Anacker DC, Gautam D, Gillespie KA, Chappell WH, Moody CA. Productive replication of human papillomavirus 31 requires DNA repair factor Nbs1. J Virol. 2014 Aug;88(15):8528-44. doi: 10.1128/JVI.00517-14. Epub 2014 May 21. PMID: 24850735; PMCID: PMC4135936.

Anacker D, Moody C. Generation of organotypic raft cultures from primary human keratinocytes. J Vis Exp. 2012 Feb 22;(60):3668. doi: 10.3791/3668. PMID: 22395296; PMCID: PMC3376940.

Gillespie KA, Mehta KP, Laimins LA, Moody CA. Human papillomaviruses recruit cellular DNA repair and homologous recombination factors to viral replication centers. J Virol. 2012 Sep;86(17):9520-6. doi: 10.1128/JVI.00247-12. Epub 2012 Jun 27. PMID: 22740399; PMCID: PMC3416172.

Knight GL, Pugh AG, Yates E, Bell I, Wilson R, Moody CA, Laimins LA, Roberts S. A cyclin-binding motif in human papillomavirus type 18 (HPV18) E1^E4 is necessary for association with CDK-cyclin complexes and G2/M cell cycle arrest of keratinocytes, but is not required for differentiation-dependent viral genome amplification or L1 capsid protein expression. Virology. 2011 Mar 30;412(1):196-210. doi: 10.1016/j.virol.2011.01.007. Epub 2011 Jan 31. PMID: 21276999; PMCID: PMC3722429.

Moody CA, Laimins LA. Human papillomavirus oncoproteins: pathways to transformation. Nat Rev Cancer. 2010 Aug;10(8):550-60. doi: 10.1038/nrc2886. Epub 2010 Jul 1. PMID: 20592731.

Fradet-Turcotte A, Moody C, Laimins LA, Archambault J. Nuclear export of human papillomavirus type 31 E1 is regulated by Cdk2 phosphorylation and required for viral genome maintenance. J Virol. 2010 Nov;84(22):11747-60. doi: 10.1128/JVI.01445-10. Epub 2010 Sep 15. PMID: 20844047; PMCID: PMC2977856.

Moody CA, Laimins LA. Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation. PLoS Pathog. 2009 Oct;5(10):e1000605. doi: 10.1371/journal.ppat.1000605. Epub 2009 Oct 2. PMID: 19798429; PMCID: PMC2745661.

Côté-Martin A, Moody C, Fradet-Turcotte A, D'Abramo CM, Lehoux M, Joubert S, Poirier GG, Coulombe B, Laimins LA, Archambault J. Human papillomavirus E1 helicase interacts with the WD repeat protein p80 to promote maintenance of the viral genome in keratinocytes. J Virol. 2008 Feb;82(3):1271-83. doi: 10.1128/JVI.01405-07. Epub 2007 Nov 21. PMID: 18032488; PMCID: PMC2224424.

Moody CA, Fradet-Turcotte A, Archambault J, Laimins LA. Human papillomaviruses activate caspases upon epithelial differentiation to induce viral genome amplification. Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19541-6. doi: 10.1073/pnas.0707947104. Epub 2007 Nov 28. PMID: 18048335; PMCID: PMC2148325.

Stewart S, Dawson CW, Takada K, Curnow J, Moody CA, Sixbey JW, Young LS. Epstein-Barr virus-encoded LMP2A regulates viral and cellular gene expression by modulation of the NF-kappaB transcription factor pathway. Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15730-5. doi: 10.1073/pnas.0402135101. Epub 2004 Oct 21. PMID: 15498875; PMCID: PMC524829.

Moody CA, Scott RS, Su T, Sixbey JW. Length of Epstein-Barr virus termini as a determinant of epithelial cell clonal emergence. J Virol. 2003 Aug;77(15):8555-61. doi: 10.1128/jvi.77.15.8555-8561.2003. PMID: 12857925; PMCID: PMC165260.